6-羥基黃酮
外觀
6-Hydroxyflavone | |
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IUPAC名 6-hydroxy-2-phenylchromen-4-one | |
別名 | 6-Monohydroxyflavone; 6-Hydroxy-2-phenyl-4-benzopyrone |
識別 | |
CAS號 | 6665-83-4 ![]() |
PubChem | 72279 |
ChemSpider | 65233 |
SMILES |
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InChI |
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InChIKey | GPZYYYGYCRFPBU-UHFFFAOYAV |
KEGG | C14137 |
性質 | |
化學式 | C15H10O3 |
摩爾質量 | 238.24 g·mol−1 |
密度 | 1.411 g·cm−3[1] |
熔點 | 235.5—236.5 °C(508.6—509.6 K)[2] |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
6-羥基黃酮(英語:6-Hydroxyflavone)是一種黃酮類化合物,是細胞色素P450酶CYP2C9的非競爭性抑制劑。6-羥基黃酮可在黃花假杜鵑(學名:Barleria prionitis)的葉子中發現[3], 有可能成為治療焦慮樣障礙的潛在藥物[4][5]。
參考文獻
[編輯]- ^ J. Seetharaman, S. S. Rajan. Structure of 6-hydroxyflavone. Acta Crystallographica Section C Crystal Structure Communications. 1992-09-15, 48 (9): 1714–1715 [2021-01-08]. doi:10.1107/S0108270192005456. (原始內容存檔於2018-06-02).
- ^ J. H. Looker, Walter W. Hanneman. Physical and Chemical Properties of Hydroxyflavones. I. Infrared Absorption Spectra of Monohydroxyflavones and Their O-Methyl and O-Acetyl Derivatives 1,2. The Journal of Organic Chemistry. 1962-02, 27 (2): 381–389 [2021-01-08]. ISSN 0022-3263. doi:10.1021/jo01049a010 (英語).
- ^ M Daniel. Medicinal Plants: Chemistry and Properties. Science Publishers. 2006: 78 [2021-01-08]. ISBN 978-1-57808-395-4. (原始內容存檔於2022-03-09).
- ^ Ren, Lihuan; Wang, Feng; Xu, Zhiwen; Chan, Wing Man; Zhao, Cunyou; Xue, Hong, GABAA receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone, Biochemical Pharmacology, 2010, 79 (9): 1337–1344, PMID 20067772, doi:10.1016/j.bcp.2009.12.024
- ^ 6-HYDROXYFLAVONE | CAS:6665-83-4 | Huateng Pharma | Pharmaceutical chemical reagents, PEG derivatives. en.huatengsci.com. [2020-03-27]. (原始內容存檔於2021-01-10).
外部連結
[編輯]- 6-hydroxy flavone on Plant Metabolic Network
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