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阿美雌酮

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阿美雌酮
临床资料
其他名称Ba 38372; Ciba 38372; 7α-Methylestrone
给药途径By mouth
药物类别英语Drug classEstrogen
ATC码
  • 未分配
识别信息
  • (7R,8R,9S,13S,14S)-3-hydroxy-7,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
CAS号10448-96-1  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.212.018 编辑维基数据链接
化学信息
化学式C19H24O2
摩尔质量284.40 g·mol−1
3D模型(JSmol英语JSmol
  • CC1CC2=C(C=CC(=C2)O)C3C1C4CCC(=O)C4(CC3)C
  • InChI=InChI=1S/C19H24O2/c1-11-9-12-10-13(20)3-4-14(12)15-7-8-19(2)16(18(11)15)5-6-17(19)21/h3-4,10-11,15-16,18,20H,5-9H2,1-2H3/t11-,15-,16+,18-,19+/m1/s1
  • Key:JUAJXSMWFOFDFC-MNHDCVOLSA-N

阿美雌酮(英语:Almestrone,开发阶段代号为:Ba 38372Ciba 38372,也被称为7α-甲基雌酮,7α-methylestrone)是一种人工合成甾体雌激素药物,1967年合成,从未上市[1],可作为合成其它甾体药物的前体[2][3]

另见

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参考文献

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  1. ^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 900– [2021-06-27]. ISBN 978-1-4757-2085-3. (原始内容存档于2022-10-16). 
  2. ^ Krause N, Aksin-Artok Ö. Copper-Mediated and Copper-Catalyzed Addition and Substitution Reactions of Extended Multiple Bond Systems. PATai's Chemistry of Functional Groups. 2011. ISBN 9780470682531. doi:10.1002/9780470682531.pat0450. 
  3. ^ Morais GR, Yoshioka N, Watanabe M, Mataka S, Oliveira CD, Thiemann T. C7-Substituted Estranes and Related Steroids. Mini-Reviews in Organic Chemistry. 2006, 3 (3): 229–251. ISSN 1570-193X. doi:10.2174/1570193X10603030229.